Temperature preference differences between strains of Mus musculus, associated variables, and ecological...

Area of Science:

• Behavioral Ecology
• Animal Physiology
• Genetics

Background:

• Temperature preference is a critical factor in habitat selection for endotherms.
• Inbred mouse strains exhibit genetic variation that can influence physiological and behavioral traits.
• Understanding the genetic basis of thermoregulation and its correlates is essential for ecological adaptation studies.

Purpose of the Study:

• To investigate temperature preference differences among inbred mouse strains and their hybrids.
• To identify morphological and physiological correlates of temperature preference.
• To examine developmental changes and genotype-specific variations in temperature preference and associated traits.

Main Methods:

• Assessed temperature preference in three inbred mouse strains (Balb/c, C3H, C57Bl) and their hybrids.
• Measured body weight, body temperature, hair density, and tail length at two age points (juvenile and adult).
• Analyzed developmental changes and genotype-by-age interactions for all measured traits.

Main Results:

• Significant differences in temperature preference were observed among inbred strains, with Balb/c preferring lower temperatures.
• Mice selecting cooler temperatures were heavier, had higher body temperatures, and lower hair density.
• Preferred temperature decreased with age, and developmental trajectories varied significantly by genotype.

Conclusions:

• Temperature preference is a heritable, adaptive trait influenced by genotype, with associated morphological and physiological correlates.
• These traits are likely under stabilizing selection to optimize habitat selection for specific populations.
• Tail length showed overdominance and a less consistent association with temperature preference compared to other traits.