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Molecular epidemiology of OHIO-1 beta-lactamase
M A Kron1, D M Shlaes, C Currie-McCumber
1Infectious Diseases Section, Cleveland Veterans Administration Medical Center, Ohio.
Antimicrobial Agents and Chemotherapy
|December 1, 1987
Abstract:
A total of 31 plasmids, all bearing a gene that encodes a novel, plasmid-mediated Richmond-Sykes class III beta-lactamase designated OHIO-1 and a gene that encodes aminoglycoside 2"-adenyltransferase, have been collected from hospitals in Ohio. By using restriction endonuclease digestion and Southern hybridization, we were able to demonstrate that all these plasmids have a common genetic origin.