Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Matrix and mineral changes in developing enamel.

C Robinson, H D Briggs, P J Atkinson

    Journal of Dental Research
    |March 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Subunit structures in hydroxyapatite crystal development in enamel: implications for amelogenesis imperfecta.

    Connective tissue research·2003
    Same author

    Maggots and wound healing: an investigation of the effects of secretions from Lucilia sericata larvae upon interactions between human dermal fibroblasts and extracellular matrix components.

    The British journal of dermatology·2003
    Same author

    Apertureless near-field Raman spectroscopy.

    Journal of microscopy·2003
    Same author

    Daily use of dentifrice with and without xylitol and fluoride: effect on glucose retention in humans in vivo.

    Archives of oral biology·2003
    Same author

    The osteodystrophy of mucolipidosis type III and the effects of intravenous pamidronate treatment.

    Journal of inherited metabolic disease·2003
    Same author

    Organic material and the optical properties of the dark zone in caries lesions of enamel.

    European journal of oral sciences·2003
    Same journal

    Gold Nanoparticles Enhance the Antibacterial and Osteogenic Properties of Polyetheretherketone.

    Journal of dental research·2026
    Same journal

    Periodontitis-Aggravated Diabetic Kidney Disease with Altered Glycolysis.

    Journal of dental research·2026
    Same journal

    Response to Letter to Editor: "Estimating the Individualized Effect of Tooth Extraction before Radiotherapy on Osteoradionecrosis Using Causal Machine Learning".

    Journal of dental research·2026
    Same journal

    Reorienting Oral Health Promotion through Systems Thinking.

    Journal of dental research·2026
    Same journal

    <i>Porphyromonas gingivalis</i>-Induced NETs Mediate Neuroinflammation via TLR4 Activation.

    Journal of dental research·2026
    Same journal

    Oral Burden of Sjögren Disease: A Systematic Review and Meta-analysis.

    Journal of dental research·2026
    See all related articles

    Enamel development involves matrix changes and selective amelogenin loss before mineralization. Mineral ions increase as organic matrix is lost and replaced by water in developing rat and bovine incisors.

    Area of Science:

    • Biochemistry
    • Developmental Biology
    • Mineralization

    Background:

    • Enamel formation is a complex biomineralization process.
    • The enamel matrix undergoes significant changes during development.
    • Understanding these changes is crucial for dental health.

    Purpose of the Study:

    • To investigate changes in enamel and the enamel organ during development.
    • To analyze the molecular and ionic composition shifts during enamel matrix formation and degradation.
    • To correlate matrix changes with mineral deposition in developing incisors.

    Main Methods:

    • Analysis of small tissue samples from developing rat and bovine incisors.
    • Examination of enamel matrix components and mineral ion concentrations.

    Related Experiment Videos

  • Assessment of molecular weight changes and ion ratios (Ca/P, F, Mg, CO3, 32PO4).

    • Main Results:

    • Selective loss of amelogenin components occurred before secondary mineralization.
    • A slight increase in smaller molecular weight components suggested limited matrix breakdown.
    • Mineral ion concentration increased steeply after organic matrix removal.
    • Minor inorganic ion concentrations (F, Mg, CO3) decreased during development.
    • Ions like fluoride and phosphate penetrated and concentrated in enamel as water replaced lost matrix.

    Conclusions:

    • Enamel development is characterized by selective matrix component loss and subsequent mineralization.
    • The replacement of organic matrix with water facilitates ion uptake prior to rapid mineralization.
    • These findings provide insights into the intricate process of tooth enamel formation.