Coronary Endarterectomy or Patch Angioplasty for Diffuse Left Anterior Descending Artery Disease
Ohad Bitan1,2, Paul A Pirundini3, Eyal Leshem1,2
1Department of Internal Medicine C, The Chaim Sheba Medical Center, Tel Hashomer, Israel.
Insights
Coronary endarterectomy and patch angioplasty offer comparable outcomes for severe left anterior descending artery disease. Endarterectomy significantly reduces the need for future interventions compared to patch angioplasty.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
Background:
- Coronary endarterectomy and patch angioplasty are adjuncts to surgical revascularization for severe coronary lesions.
- These techniques are applied to the left anterior descending (LAD) artery.
Purpose of the Study:
- To review the short- and long-term results of endarterectomy versus patch angioplasty for LAD artery disease.
- To compare the efficacy and outcomes of these two surgical methods.
Main Methods:
- Retrospective review of 166 patients undergoing internal thoracic artery grafting to the LAD.
- Comparison between patients receiving adjunct endarterectomy (95) and patch angioplasty (71) between 2002 and 2014.
Main Results:
- Endarterectomy patients were older and had fewer recent myocardial infarctions.
- Longer bypass and cross-clamp times were observed in the endarterectomy group.
- No significant differences in mortality, perioperative myocardial infarction, or long-term survival were found.
- Freedom from percutaneous coronary intervention was significantly higher in the endarterectomy group at 1 and 5 years.
Conclusions:
- Endarterectomy and patch angioplasty are comparable for complete revascularization in selected patients with diffuse LAD atherosclerotic disease.
- Endarterectomy, involving complete plaque extraction, yields similar short-term and long-term survival to patch angioplasty.
- Endarterectomy significantly reduces the requirement for future interventions compared to patch angioplasty.
Background:
Coronary endarterectomy and patch angioplasty for the left anterior descending (LAD) artery have been shown to be effective adjunct techniques to surgical revascularization for severe coronary lesions. The objective of this study is to review the short- and long-term results of these two methods in our institution.
Methods:
We retrospectively reviewed 166 consecutive patients who underwent internal thoracic artery grafting to the LAD, with either adjunct endarterectomy (95 patients) or patch angioplasty (71 patients) between 2002 and 2014. We compared the early and late outcomes between groups.
Results:
The endarterectomy patients were older than the patch angioplasty patients (71 vs. 67 years, p = 0.007) and had lower rates of recent myocardial infarction (25% vs. 45%, respectively, p = 0.008). Median pulmonary bypass times and aortic cross clamp times were significantly longer in the endarterectomy group compared with the patch angioplasty group by 47 minutes (p < 0.001) and 42 minutes (p < 0.001), respectively. Median follow-up time was 6.9 years. No significant differences in operative mortality, perioperative myocardial infarction, and long-term survival were found. Freedom from percutaneous coronary intervention at 1 and 5 years was significantly higher in the endarterectomy group compared with the patch angioplasty group (p = 0.002).
Conclusions:
Endarterectomy and patch angioplasty are comparable methods to reach complete revascularization for highly selected patients with diffuse atherosclerotic disease in the LAD. Compared with patch angioplasty, complete extraction of the atherosclerotic plaque with an endarterectomy leads to similar short-term outcomes and long-term survival while significantly reducing the need for further interventions in the future.
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