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Biologics, derived from living sources such as humans, animals, or microorganisms, represent a significant category of pharmaceuticals. These complex molecules, developed through advanced biotechnological methods or purified from natural sources, include essential medical treatments like insulin and growth hormones. The complexity of biologics arises from their large molecular structures and the intricate processes required for their production, making them distinct from conventional...
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Biosimilars: Considerations for Oncology Nurses
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Vida Vizgirda1, Ira Jacobs2

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Clinical Journal of Oncology Nursing
|March 19, 2017
PubMed
Summary
This summary is machine-generated.

Biosimilars are highly similar to biologics but have different regulatory pathways. Oncology nurses play a key role in educating clinicians and patients about biosimilar use for safe and effective cancer care.

Keywords:
biologicsbiosimilarsclinical practiceoncologypostmarketing safety

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Area of Science:

  • Oncology
  • Pharmacology
  • Biotechnology

Background:

  • Biosimilars are similar to licensed biologics and treat the same conditions.
  • Increasing approval and use of biosimilars necessitate awareness among oncology nurses.

Purpose of the Study:

  • Review biosimilar properties, regulation, and approval processes.
  • Evaluate quality, safety, and efficacy of biosimilars.
  • Discuss postmarketing surveillance and significance for oncology nursing.

Main Methods:

  • Literature search of PubMed and regulatory agency websites.
  • Focused on biosimilar development and use in oncology.

Main Results:

  • Biosimilars are not generic equivalents to biologics due to molecular complexity.
  • Biosimilar regulatory approval differs from small-molecule generics.
  • Oncology nurses are crucial for educating stakeholders on biosimilar understanding and safe use.

Conclusions:

  • Oncology nurses require specialized knowledge regarding biosimilars.
  • Education is vital for optimal and safe utilization of biosimilars in cancer care.
  • Nurses can bridge knowledge gaps for clinicians and patients regarding biosimilars.