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Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging
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[Relationship between multi-slice spiral CT angiography imaging features and in-hospital death of patients with

Z Y Xiao1, H J Wang, C L Yao

  • 1Department of Emergency, Zhongshan Hospital Affiliated to Fudan University, Shanghai 200032, China.

Zhonghua Xin Xue Guan Bing Za Zhi
|March 21, 2017
PubMed

Insights

Multi-slice spiral CT angiography (CTA) effectively visualizes aortic dissection (AD) and its complications. The number of involved branch vessels and the extent of false lumen tearing are key predictors of in-hospital death in AD patients.

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Thoracic Surgery

Background:

  • Aortic dissection (AD) is a life-threatening condition requiring accurate diagnosis and risk stratification.
  • Multi-slice spiral CT angiography (CTA) is a primary imaging modality for evaluating AD.
  • Understanding imaging predictors of mortality is crucial for patient management.

Purpose of the Study:

  • To investigate the imaging manifestations of AD using multi-slice spiral CTA.
  • To determine the relationship between CTA findings and in-hospital mortality in AD patients.
  • To identify independent imaging risk factors for in-hospital death in AD.

Main Methods:

  • Retrospective analysis of 429 patients with AD who underwent CTA.
  • Classification of patients into operation and non-operation groups.
  • Multivariate logistic regression analysis to assess the association between imaging features and in-hospital death.

Main Results:

  • CTA clearly depicted AD, true/false lumens, intimal tears (84.62%), calcification (14.69%), and thrombosis (52.91%).
  • In-hospital mortality was significantly higher in the non-operation group (47.46%) vs. operation group (3.24%).
  • Number of involved branch vessels and false lumen tearing range were independent predictors of in-hospital death.

Conclusions:

  • Multi-slice spiral CTA provides comprehensive visualization of AD and its key features.
  • The number of involved branch vessels and the extent of false lumen tearing are significant independent risk factors for in-hospital mortality in AD patients.
  • These imaging findings can aid in risk stratification and treatment decisions for AD.

Keywords:
Aortic diseasesPrognosisTomography, spiral computed

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