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Hemolytic uremic syndrome in a patient with small cell lung cancer
L Avvento1, S Gordon, J M Silberberg
1Division of Hematology, State University of New York at Stony Brook.
American Journal of Hematology
|March 1, 1988
Abstract:
Hemolytic uremic syndrome is a rare entity in patients with carcinoma and presents with a triad of renal insufficiency, microangiopathic hemolytic anemia, and thrombocytopenia. We report this syndrome for the first time in a patient with small cell lung carcinoma. Spontaneous platelet aggregation of washed normal platelets was demonstrated using patient plasma. Circulating immune complex levels were not elevated. The entity completely resolved after treatment with plasma, vincristine, aspirin, and dipyridamole.