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Organ donor management: Eight common recommendations and actions that deserve reflection
C Chamorro-Jambrina1, M R Muñoz-Ramírez2, J L Martínez-Melgar3
1Servicio de Medicina Intensiva, HU Puerta de Hierro-Majadahonda, Majadahonda, Madrid, Spain.
Medicina Intensiva
|March 21, 2017
Summary
This review examines organ donor management in brain death (BD), clarifying controversies in protocols for catecholamine storms, vasoactive drugs, and hemodynamic monitoring to improve donor care and organ viability.
Area of Science:
- Critical Care Medicine
- Nephrology
- Transplantation
Background:
- Understanding brain death (BD) pathophysiology has advanced, yet controversies persist regarding optimal organ donor management protocols.
- Existing reviews offer conflicting recommendations, some not applicable to general critical care patients.
Purpose of the Study:
- To review recent publications impacting controversial measures in organ donor management.
- To provide evidence-based insights to confirm, refute, or guide new research in BD donor care.
Main Methods:
- Comprehensive review of recent scientific literature and publications.
- Analysis of studies related to controversial aspects of brain death donor management.
Main Results:
- Identified key areas of controversy including catecholamine storm management, vasoactive drug use, and hemodynamic monitoring.
- Highlighted the need to discard recommendations lacking physiopathological basis.
Conclusions:
- Evidence-based review supports refining organ donor management protocols in brain death.
- Future research should focus on physiopathological principles to guide donor care and improve organ donation outcomes.
Keywords:
Brain deathCatecholamine stormEchocardiogramEcocardiogramaEnteral nutritionFármacos vasoactivosHipotermiaHormonal supplementationHypothermiaMechanical ventilationMonitoringMonitorizaciónMuerte encefálicaNutrición enteralOrgan donor managementReposición hormonalTormenta catecolamínicaTratamiento del donante de órganosVasoactive drugsVentilación mecánica
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