Anesthesia in patients with infectious disease caused by multi-drug resistant bacteria
Sharon Einav1, Yonit Wiener-Well
1aThe Surgical Intensive Care Unit bThe Infectious Disease Unit, Shaare Zedek Medical Center and the Hebrew University, Faculty of Medicine, Jerusalem, Israel.
Purpose Of Review:
Up to 50% of specific bacterial strains in healthcare admission facilities are multi-drug resistant organisms (MDROs). Involvement of anesthesiologists in management of patients carrying/at risk of carrying MDROs may decrease transmission in the Operating Room (OR).
Recent Findings:
Anesthesiologists, their work area and tools have all been implicated in MDRO outbreaks. Causes include contamination of external ventilation circuits and noncontribution of filters to prevention, inappropriate decontamination procedures for nondisposable equipment (e.g. laryngoscopes, bronchoscopes and stethoscopes) and the anesthesia workplace (e.g. external surfaces of cart and anesthesia machine, telephones and computer keyboards) during OR cleaning and lack of training in sterile drug management.
Summary:
Discussions regarding the management of potential MDRO carriers must include anesthesia providers to optimize infection control interventions as well as the anesthesia method, the location of surgery and recovery and the details of patient transport. Anesthesia staff must learn to identify patients at risk for MDRO infection. Antibiotic prophylaxis, although not evidence based, should adhere to known best practices. Adjuvant therapies (e.g. intranasal Mupirocin and bathing with antiseptics) should be considered. Addition of nonmanual OR cleaning methods such as ultraviolet irradiation or gaseous decontamination is encouraged. Anesthesiologists must undergo formal training in sterile drug preparation and administration.
Insights
Anesthesiologists can reduce multi-drug resistant organism (MDRO) transmission in operating rooms. Proper training and sterile techniques are crucial for anesthesia providers managing patients at risk of MDRO infection.
Area of Science:
- Infection Control
- Anesthesiology
- Microbiology
Background:
- Multi-drug resistant organisms (MDROs) are prevalent in healthcare settings, with up to 50% of certain bacterial strains exhibiting resistance.
- Anesthesiologists play a role in managing patients carrying or at risk of carrying MDROs, potentially impacting transmission within the Operating Room (OR).
Purpose of the Study:
- To highlight the critical role of anesthesiologists in preventing MDRO transmission within the OR.
- To emphasize the need for including anesthesia providers in discussions and strategies for managing patients with or at risk of MDROs.
Main Methods:
- Review of current literature and outbreak investigations implicating anesthesiologists and their environment in MDRO transmission.
- Analysis of contamination sources and procedural gaps in anesthesia practice related to MDROs.
- Evaluation of infection control interventions and training needs for anesthesia staff.
Main Results:
- Anesthesia providers, equipment, and the OR environment (ventilation circuits, non-disposable equipment, workstations) have been identified as potential sources of MDRO transmission.
- Inadequate decontamination procedures and lack of training in sterile drug management contribute to MDRO spread.
- Current practices may not sufficiently address the risks associated with MDRO carriers in the perioperative setting.
Conclusions:
- Anesthesia providers must be integral to developing and implementing infection control strategies for MDRO carriers.
- Formal training in sterile drug handling and identification of at-risk patients is essential for anesthesia staff.
- Enhanced environmental cleaning methods (e.g., UV irradiation) and consideration of adjuvant therapies may further reduce MDRO transmission.
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