Related Experiment Video
Updated: Mar 6, 2026
A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
The Utility of 68Ga-PSMA PET/CT in Poorly Differentiated Metastatic Prostate Cancer
Mehmet Onur Demirkol1, Murat Can Kiremit, Omer Acar
1From the *Department of Nuclear Medicine and Molecular Imaging, School of Medicine, Koc University; †Department of Nuclear Medicine and Molecular Imaging, VKF American Hospital; ‡Department of Urology, Koc University Hospital; and §Department of Pathology, School of Medicine, Acibadem University, Istanbul, Turkey.
Abstract:
We aimed to emphasize how useful PSMA PET/CT findings can be while trying to restage prostate cancer after radical prostatectomy in the presence of low prostate-specific antigen values. A 64-year-old man with pT3b N1 M0 Gleason 7 adenocarcinoma of the prostate presented 5 years postoperatively with a palpable axillary mass, whereas his prostate-specific antigen was 0.08 ng/mL. Conventional imaging studies and histopathologic findings of the axillary mass biopsy revealed inconclusive results. Ga-PSMA PET/CT demonstrated PSMA-positive metastatic lesions, the largest one being located in the right axilla. This finding confirmed metastatic poorly differentiated prostate cancer, and androgen deprivation therapy was initiated.
