Related Experiment Video
Updated: Sep 27, 2026

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice
Published on: October 24, 2018
[Role of the peripheral catecholaminergic systems in the antistress action of neuropeptides]
Abstract:
The mediator activity of the peripheral catecholaminergic systems (the adrenergic nerves of dura mater and the concentrations of noradrenaline and adrenaline in the adrenals of rats) during dynamic and immobilization stress was investigated with the help of fluorescent microscopy and spectrofluorometry. Neuropeptides--dalargin and another enkephalin analog--were injected intraperitoneally, 150 mg/kg. A visible antistress action of these neuropeptides has been demonstrated, it was more marked after treatment with dalargin. The role of peripheral catecholaminergic system in the mechanism of stress-protective effects of neuropeptides is discussed.
Related Concept Videos
The Sympathetic Nervous System
Hypothalamic-Pituitary Axis
Adrenergic Neurons: Neurotransmission
Synthesis: Catecholamine synthesis requires tyrosine, which is taken...
Sympathetic Signaling
Sympathetic preganglionic fibers release the neurotransmitter acetylcholine (ACh) onto the ganglionic neurons in the...
Sympathetic Activation
Physiological Foundation of Stress
Role of the Sympathetic Nervous System
Adrenaline triggers the...

