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Association Between Severe Vitamin D Deficiency, Lung Function and Asthma Control.

Seda Beyhan-Sagmen1, Ozgur Baykan1, Baran Balcan1

  • 1Department of Pulmonolgy and Intensive care, Faculty of Medicine, Marmara University , Estambul, Turquía.

Archivos De Bronconeumologia
|March 22, 2017
PubMed
Summary

Severe vitamin D deficiency is common in Turkish adults with asthma. Low vitamin D levels correlate with poorer asthma control and reduced lung function, indicating a significant health concern.

Keywords:
Asthma controlControl del asmaDéficit grave de vitamina DFEV(1)Función pulmonarPulmonary functionSevere vitamin D deficiency

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Area of Science:

  • Pulmonary Medicine
  • Endocrinology
  • Clinical Research

Background:

  • Asthma affects a significant portion of the adult population.
  • Vitamin D deficiency is a widespread condition with potential health implications.
  • The interplay between vitamin D status, asthma control, and lung function requires further investigation.

Purpose of the Study:

  • To investigate the association between severe vitamin D deficiency and asthma control in Turkish adults.
  • To examine the relationship between vitamin D levels and pulmonary function in asthmatic patients.
  • To determine the prevalence of severe vitamin D deficiency in this population.

Main Methods:

  • A cohort of 106 adult asthma patients was studied.
  • Pulmonary function tests, allergy assessments, and biochemical markers including vitamin D levels were measured.
  • Patients were categorized into subgroups based on vitamin D levels (<10 ng/ml vs. ≥10 ng/ml).

Main Results:

  • 66% of patients exhibited severe vitamin D deficiency (<10 ng/ml).
  • Lower vitamin D levels were significantly associated with reduced forced expiratory volume in 1 second (FEV1).
  • Severe vitamin D deficiency correlated with poorer asthma control and increased inhaled corticosteroid use.

Conclusions:

  • The prevalence of severe vitamin D deficiency is high among adult Turkish asthmatics.
  • Low vitamin D levels are linked to impaired pulmonary function and inadequate asthma control.
  • These findings highlight the importance of assessing and managing vitamin D status in asthma patients.