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Multiple Metastasizing Pleomorphic Adenomas of the Lung
Ayaka Nakai1, Kensuke Suzuki, Hideaki Furuse
1Department of Internal Medicine, Toyama Prefectural Central Hospital, Japan.
Internal Medicine (Tokyo, Japan)
|March 22, 2017
Summary
Metastatic pleomorphic adenoma, a rare lung tumor, can arise years after parotid gland surgery. This case highlights the importance of considering extraglandular metastasis in patients with a history of pleomorphic adenoma.
Area of Science:
- Oncology
- Pulmonary Medicine
- Pathology
Background:
- Pleomorphic adenoma is the most common salivary gland tumor.
- Metastasis from pleomorphic adenoma is rare, especially to the lungs.
Observation:
- A 40-year-old woman presented with abnormal chest X-ray findings.
- History of pleomorphic adenoma of the parotid gland treated 12 years prior.
- Chest CT revealed bilateral lung nodules.
Findings:
- Surgical resection and histopathological examination confirmed metastatic pleomorphic adenoma of the lung.
- This represents a rare extraglandular metastasis.
Implications:
- Highlights the potential for late metastasis of pleomorphic adenoma.
- Emphasizes the need for vigilance in patients with a history of pleomorphic adenoma.
- Suggests considering pleomorphic adenoma in the differential diagnosis of lung nodules in select patients.

