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Updated: Mar 6, 2026

Enhancing Tumor Content through Tumor Macrodissection
Published on: February 12, 2022
Primary adrenal diffuse large B-cell lymphoma positive for CD5 and CD10
Yoshikazu Yamamoto1, Yuichi Sumii, Yutaro Shiraishi
1Department of Hematology and Oncology, Okayama City Hospital.
Abstract:
A 69-year-old man presented with back pain over the prior few months and was hospitalized because of bilateral adrenal masses and fracture of the left sixth rib. The mass on the right measured 6.5×3.6×7.0 cm, that on the left 8.1×4.8×6.9 cm, on CT. The final diagnosis was CD5- and CD10-positive primary adrenal diffuse large B-cell lymphoma (PA-DLBCL) with rib involvement. After EPOCH therapy accompanied with rituximab and intrathecal treatment, the tumors decreased dramatically. However, he died due to disease progression 8 months after the diagnosis. The prognosis of CD5- and CD10-positive PA-DLBCL may be very poor even with rituximab-containing chemotherapy.
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