Related Experiment Videos
Management and risk factor control of coronary artery disease in elderly versus nonelderly: a multicenter registry
Arintaya Phrommintikul1, Rungroj Krittayaphong2, Wanwarang Wongcharoen1
1Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Insights
Elderly patients with coronary artery disease (CAD) showed equitable treatment and better risk factor goal attainment, except for blood pressure, compared to younger patients. This registry highlights effective management strategies for older adults with CAD.
Area of Science:
- Cardiology
- Geriatrics
- Public Health
Background:
- Coronary artery disease (CAD) significantly impacts the elderly, with aging being a major risk factor for atherosclerosis and adverse outcomes.
- Suboptimal control of risk factors in elderly CAD patients may stem from underutilization of guideline-directed therapies.
- Understanding management disparities and goal attainment is crucial for improving care in this demographic.
Purpose of the Study:
- To compare the management, risk factor control, and goal attainment of coronary artery disease (CAD) in elderly versus nonelderly patients.
- To investigate potential inequities in CAD treatment based on age.
Main Methods:
- Analysis of data from the CORE-Thailand registry, a prospective, multicenter observational study.
- Comparison of 2172 elderly (≥ 65 years) and 1948 nonelderly (< 65 years) CAD patients.
- Evaluation of treatment patterns, medication use, and risk factor goal achievement.
Main Results:
- Elderly CAD patients exhibited higher rates of hypertension, dyslipidemia, atrial fibrillation, and chronic kidney disease.
- Coronary revascularization rates were similar between elderly and nonelderly groups.
- Goal attainment for glycemic control, LDL cholesterol, and smoking cessation was higher in the elderly, excluding blood pressure control.
Conclusions:
- The CORE-Thailand registry indicates equitable treatment for CAD in elderly and nonelderly populations.
- Elderly CAD patients achieved higher success rates in risk factor control, with the exception of blood pressure targets.
- Further analysis of this cohort will elucidate the impact of goal attainment on cardiovascular outcomes.
Background:
Coronary artery disease (CAD) is a leading cause of death in elderly because aging is the important non-modifiable risk factors of atherosclerosis and also a predictor of poor outcomes. Underuse of guideline directed therapy may contribute to suboptimal risk factor control and worse outcomes in the elderly. We aimed to explore the management of CAD, risk factors control as well as goal attainment in elderly compared to nonelderly CAD patients.
Methods:
The CORE-Thailand is an ongoing multicenter, prospective, observational registry of patients with high atherosclerotic risk in Thailand. The data of 4120 CAD patients enrolled in this cohort was analyzed comparing between the elderly (age ≥ 65 years) vs. nonelderly (age < 65 years).
Results:
There were 2172 elderly and 1948 nonelderly patients. The elderly CAD patients had higher prevalence of hypertension, dyslipidemia, atrial fibrillation and chronic kidney disease. The proportion of patients who received coronary revascularization was not different between the elderly and nonelderly CAD patients. Antiplatelets were prescribed less in the elderly while statin was prescribed in the similar proportion. Goal attainments of risk factor control of glycemic control, low density lipoprotein cholesterol, and smoking cessation except the blood pressure goal were higher in the elderly CAD patients.
Conclusions:
The CORE-Thailand registry showed the equity in the treatment of CAD between elderly and non-elderly. Elderly CAD patients had higher rate of goal attainment in risk factor control except blood pressure goal. The effects of goal attainment on cardiovascular outcomes will be demonstrated from ongoing cohort.
Related Concept Videos
Coronary Artery Disease IV: Preventive Measures
Atherosclerosis III: Management
Coronary Artery Disease V: Interprofessional Care
Rheumatic Heart Disease III: Medical Management
Angina IV: Management
Atherosclerosis IV: Nursing Management