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[Sexual dysfunction associated with psychotropic drugs and treatment options]
M Berner1,2
1Klinik für Psychiatrie und Psychotherapeutische Medizin, Städtisches Klinikum Karlsruhe, Kaiserallee 10, 76133, Karlsruhe, Deutschland. Michael.Berner@klinikum-karlsruhe.de.
Background:
Sexual dysfunction associated with psychotropic drugs is a threat to patient quality of life and a major reason for non-compliance. Psychotropic agents can impair the sexual response in different ways due to their neurobiological mode of action.
Objective:
Presentation of the frequencies of sexual functional disorders for selected psychopharmacological groups and the available treatment modalities.
Methods:
Literature search, selection and review of relevant studies.
Results:
The most relevant groups for impairments are antidepressants and antipsychotics due to the serotonin agonistic and anti-dopaminergic properties as well as the prolactin increasing characteristics. Agents with a favorable side effects profile are now available. All phases of the sexual response are affected.
Discussion:
The treatment of psychiatric disorders should follow a comprehensive treatment plan that anticipates a likely sexual dysfunction at the initiation of treatment. The main aim is improvement of the underlying primary disorder. Some limited evidence-based treatment strategies are available.
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