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What is new in 2017? Update on fertility preservation in cancer patients

Katharina Winkler-Crepaz1, Bettina Böttcher2, Bettina Toth2

  • 1Department of Gynecological Endocrinology and Reproductive Medicine, Innsbruck Medical University, Innsbruck, Austria - katharina.winkler@i-med.ac.at.

Minerva Endocrinologica
|March 22, 2017
PubMed

Insights

Fertility preservation methods are crucial for both cancer patients and those with non-malignant conditions. This review updates on current clinical fertility preservation techniques and emerging strategies for restoring reproductive potential.

Area of Science:

  • Reproductive Medicine
  • Oncology
  • Genetics

Background:

  • Fertility preservation is increasingly vital for patients undergoing treatments causing infertility.
  • Cancer therapies and non-malignant conditions necessitate proactive fertility management.

Purpose of the Study:

  • To review current clinical fertility preservation methods.
  • To summarize advancements in novel fertility restoration strategies.

Main Methods:

  • Review of established clinical fertility preservation techniques.
  • Analysis of emerging research in reproductive science and regenerative medicine.

Main Results:

  • Current methods include oocyte/embryo cryopreservation, GnRH agonists, ovarian tissue banking, and sperm cryopreservation.
  • Investigational strategies involve in-vitro gonadal tissue culture, artificial gonads, and germline stem cell applications.

Conclusions:

  • Established fertility preservation techniques are widely available.
  • Novel approaches show promise for future fertility restoration and preservation.

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