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Correction: Altered mental status and an acid-base disturbance
Shylaja Mani1, Gregory W Rutecki2
1Department of Internal Medicine, Cleveland Clinic, Cleveland, OH, USA.
Cleveland Clinic Journal of Medicine
|March 22, 2017
Summary
This article corrects errors in a previous publication regarding osmol gap interpretation in metabolic acidosis. It clarifies how toxic ingestions can elevate the osmol gap, aiding differential diagnosis.
Area of Science:
- Medical Science
- Clinical Medicine
- Toxicology
Background:
- Anion gap metabolic acidosis requires accurate diagnostic interpretation.
- The osmol gap is a critical parameter in evaluating metabolic disturbances.
Purpose of the Study:
- To correct errors in a published table and text regarding osmol gap calculations.
- To clarify the role of the osmol gap in diagnosing multifactorial anion gap metabolic acidosis.
Main Methods:
- Review and correction of Table 2 from a prior publication.
- Revision of specific sentences within the text to improve clarity on osmol gap interpretation.
Main Results:
- Identified and corrected two errors in the original Table 2.
- Revised text emphasizes the osmol gap's utility in identifying toxic ingestions.
Conclusions:
- Accurate osmol gap interpretation is crucial for diagnosing metabolic acidosis.
- The osmol gap is increasingly valuable in the differential diagnosis of elevated anion gap metabolic acidosis due to toxic ingestions.
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