Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Endoscopic Management of Choledocholithiasis in the Elderly: Balancing Safety and Effectiveness in the Aging Era.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society·2026
Same author

Trimethoprim-Sulfamethoxazole Treatment for Severe Pertussis in Infants Younger Than 2 months During a Macrolide-Resistant Bordetella pertussis Outbreak: A Case Series.

Journal of the Pediatric Infectious Diseases Society·2026
Same author

Update on biliary endoscopy: a comprehensive review.

Expert review of gastroenterology & hepatology·2026
Same author

Emergence of mobile RND-type efflux pump gene cluster tmexCD-toprJ on a broad-host-range IncC plasmid in Shewanella species in a water environment.

Journal of global antimicrobial resistance·2026
Same author

Current status of eradication therapy and antimicrobial susceptibility testing for Helicobacter pylori in Japan: A nationwide questionnaire survey.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy·2026
Same author

Tracing the emergence of the novel fluoroquinolone resistance gene <i>qrtA</i> in enterococci through environmental reservoirs and pELF-type linear plasmids.

bioRxiv : the preprint server for biology·2026
Same journal

Detection of and Early Genomic Insights into Chikungunya Virus, Bolivia, 2025.

Emerging infectious diseases·2026
Same journal

Household Transmission of Enterovirus D68, Washington and Oregon, United States, 2022-2024.

Emerging infectious diseases·2026
Same journal

New World Ocular Dirofilariasis Caused by Dirofilaria repens Infection, United States.

Emerging infectious diseases·2026
Same journal

Angiostrongylus cantonensis Rat Lungworm Detected in Rats, Madagascar, 2022-2023.

Emerging infectious diseases·2026
Same journal

Human Pulmonary Dirofilariasis,
North Queensland, Australia, 2023<sup>1</sup>.

Emerging infectious diseases·2026
Same journal

Trends in Congenital Syphilis Cases by Maternal Country of Birth, Spain, 2016-2024.

Emerging infectious diseases·2026
See all related articles

Related Experiment Video

Updated: Mar 6, 2026

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
08:52

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

Published on: February 22, 2019

11.4K

Significant Decrease in Pertactin-Deficient Bordetella pertussis Isolates, Japan.

Yukihiro Hiramatsu, Yusuke Miyaji, Nao Otsuka

    Emerging Infectious Diseases
    |March 22, 2017
    PubMed
    Summary
    This summary is machine-generated.

    Pertactin-deficient Bordetella pertussis strains, common globally, decreased significantly in Japan from 2005-2013 to 2014-2016. This reduction correlated with evolving bacterial genotypes.

    Keywords:
    Bordetella pertussisJapanbacteriagenotypemultilocus variable-number tandem-repeat analysispertactinpertussisrespiratory infectionswhooping cough

    More Related Videos

    High-Resolution Comparison of Bacterial Conjugation Frequencies
    05:18

    High-Resolution Comparison of Bacterial Conjugation Frequencies

    Published on: January 10, 2019

    11.5K
    Improved Polymerase Chain Reaction-restriction Fragment Length Polymorphism Genotyping of Toxic Pufferfish by Liquid Chromatography/Mass Spectrometry
    09:34

    Improved Polymerase Chain Reaction-restriction Fragment Length Polymorphism Genotyping of Toxic Pufferfish by Liquid Chromatography/Mass Spectrometry

    Published on: September 20, 2016

    11.6K

    Related Experiment Videos

    Last Updated: Mar 6, 2026

    Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
    08:52

    Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

    Published on: February 22, 2019

    11.4K
    High-Resolution Comparison of Bacterial Conjugation Frequencies
    05:18

    High-Resolution Comparison of Bacterial Conjugation Frequencies

    Published on: January 10, 2019

    11.5K
    Improved Polymerase Chain Reaction-restriction Fragment Length Polymorphism Genotyping of Toxic Pufferfish by Liquid Chromatography/Mass Spectrometry
    09:34

    Improved Polymerase Chain Reaction-restriction Fragment Length Polymorphism Genotyping of Toxic Pufferfish by Liquid Chromatography/Mass Spectrometry

    Published on: September 20, 2016

    11.6K

    Area of Science:

    • Microbiology
    • Epidemiology
    • Genetics

    Background:

    • Pertussis, caused by Bordetella pertussis, is a highly contagious respiratory infection.
    • Pertactin is a key virulence factor in B. pertussis, and its absence has been noted globally.
    • Previous studies indicated a high prevalence of pertactin-lacking B. pertussis in Japan.

    Purpose of the Study:

    • To investigate the recent prevalence of pertactin-deficient Bordetella pertussis isolates in Japan.
    • To determine the association between pertactin deficiency and specific genotypes of B. pertussis.

    Main Methods:

    • Retrospective analysis of Bordetella pertussis isolates collected in Japan between 2005 and 2016.
    • Genotyping of B. pertussis isolates to identify specific genetic profiles.
    • Statistical analysis to compare the prevalence of pertactin-deficient isolates over different time periods and correlate with genotypes.

    Main Results:

    • The frequency of pertactin-deficient B. pertussis isolates in Japan significantly decreased from 41% (2005-2007) to 8% (2014-2016).
    • Intermediate frequencies were observed in 2008-2010 (35%) and 2011-2013 (25%).
    • The reduction in pertactin-deficient isolates was strongly associated with shifts in the predominant B. pertussis genotypes.

    Conclusions:

    • A notable decline in pertactin-deficient Bordetella pertussis strains has occurred in Japan.
    • Genotypic changes in B. pertussis populations are closely linked to the observed decrease in pertactin deficiency.
    • These findings highlight the dynamic evolution of B. pertussis and its implications for pertussis epidemiology.