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Updated: Mar 6, 2026
Ultrasonographic Evaluation of Breast Cancer-related Lymphedema
Published on: January 12, 2017
Lymphatic Drainage to the Paravertebral Lymph Nodes in Breast Cancer Patients
Mirela Mariana Roman1,2, Romain Barbieux2,3,4, Olivier Leduc2,5
11 Department of Mammo-Pelvic Surgery, Jules Bordet Institute , Brussels, Belgium .
Introduction:
Aberrant, altered, or blocked lymphatic drainage may contribute to the high recurrence rate of breast cancer. Thus, an efficient evaluation of lymphatic drainage from the breasts and/or upper limbs is essential in the management of lymphedema and in ipsilateral primary or contralateral recurrent breast cancer patients. There are very few reports of lymphatic drainage to the paravertebral lymph nodes in patients with a lymphedema after breast cancer surgery with or without reconstruction.
Methods:
We used lymphoscintigraphy to examine lymphatic drainage in a case series.
Results:
We observed five patients with upper limb and/or mammary lymphedema (after breast cancer surgery with or without reconstruction) who had lymphatic drainage from the upper limb or breast to the posterior intercostal and/or paravertebral lymph nodes. One patient also presented with nodal relapse at the time of our investigation.
Conclusions:
The cases from this study demonstrate the unusual, and mostly unrecognized, lymphatic drainage pathways toward lymph nodes, which may be at risk for further evolution of breast cancer.
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