Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

1.3K
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
1.3K
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

398
Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
398
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

503
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
503
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

428
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
428
Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

1.5K
Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
1.5K
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

342
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
342

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Delayed Diagnosis and Surgical Intervention of Intestinal Malrotation Can Lead to Unresolved Gastrointestinal Symptoms: Findings from a Patient-reported Registry.

Journal of pediatric surgery·2026
Same author

Availability, utilization, and barriers to bowel ultrasound for necrotizing enterocolitis: a national multidisciplinary survey.

Journal of perinatology : official journal of the California Perinatal Association·2026
Same author

Evaluating perceptions of social media professionalism by healthcare workers.

Digital health·2026
Same author

Surgical Infection Society Guidelines on the Prevention and Management of Pediatric Intra-Abdominal Infection: 2025 Update.

Surgical infections·2025
Same author

The "M" Word: Defining Malignancy in Surgical Residencies.

Journal of surgical education·2025
Same author

Non-operative management of pediatric, uncomplicated acute appendicitis: A survey of pediatric surgeons' perceptions and practice.

Journal of pediatric surgery·2025

Related Experiment Video

Updated: Mar 6, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

31.4K

Central venous access in children: indications, devices, and risks.

Guillermo Ares1, Catherine J Hunter

  • 1Division of Pediatric Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.

Current Opinion in Pediatrics
|March 22, 2017
PubMed
Summary

Ultrasound guidance and proper catheter tip placement reduce central venous catheter complications in children. Adhering to care protocols is essential for preventing infections like CLABSI.

More Related Videos

Computed Tomography (CT) Guided Implantation of a Totally Implantable Venous Access Port (TIVAP) through Subclavian Vein
05:51

Computed Tomography (CT) Guided Implantation of a Totally Implantable Venous Access Port (TIVAP) through Subclavian Vein

Published on: January 13, 2026

264
Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
09:09

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

Published on: November 3, 2023

1.6K

Related Experiment Videos

Last Updated: Mar 6, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

31.4K
Computed Tomography (CT) Guided Implantation of a Totally Implantable Venous Access Port (TIVAP) through Subclavian Vein
05:51

Computed Tomography (CT) Guided Implantation of a Totally Implantable Venous Access Port (TIVAP) through Subclavian Vein

Published on: January 13, 2026

264
Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
09:09

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

Published on: November 3, 2023

1.6K

Area of Science:

  • Pediatric critical care medicine
  • Vascular access devices
  • Infection control

Background:

  • Central venous catheters (CVCs) are vital for neonates and children's diagnosis and therapy.
  • Reducing complications, especially central line-associated bloodstream infections (CLABSIs), is a key focus for healthcare systems.

Purpose of the Study:

  • To review indications for CVC use and available devices.
  • To highlight best practices and future research for minimizing CVC complications.

Main Methods:

  • Systematic reviews of randomized trials.
  • Analysis of recent randomized trials in pediatric CVCs.
  • Review of evidence on CVC placement techniques and infection prevention strategies.

Main Results:

  • Ultrasound guidance for CVC placement in children is safer than blind techniques for internal jugular vein access.
  • Appropriate catheter tip placement correlates with fewer complications.
  • Ethanol lock prophylaxis and antibiotic-coated CVCs show promise in reducing CLABSI rates.

Conclusions:

  • While landmark techniques remain valid, ultrasound guidance improves CVC placement safety.
  • Strict adherence to CVC care protocols is crucial for preventing infectious complications.