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Published on: March 8, 2012
Human papillomavirus type 2 DNA in oral and labial verruca vulgaris
L R Eversole1, P J Laipis, T L Green
1Department of Oral Diagnostic Sciences, University of Florida, Gainesville 32610.
Abstract:
Twenty instances of verruca vulgaris, equally divided between oral mucosa and lip vermillion, were assayed for the presence of human papillomavirus (HPV) capsid antigen and type-specific DNA employing in situ hybridization methods. All 10 cases arising on lip vermillon expressed capsid antigen and harbored HPV Type 2 genomes as assessed under conditions of high stringency DNA hybridization. Oral verrucae rarely expressed capsid antigen; HPV Type 2 genomes were encountered in 20% of the cases.
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