Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Administration of Topical NorLeu<sup>3</sup>Angiotensin(1-7) Minimizes Fibrotic Corneal Healing in Stellate Wound: A 28-Day Study.

International journal of molecular sciences·2026
Same author

Value of Treatment for Combat Ocular Trauma.

Military medicine·2025
Same author

In vivo microstimulation stability of electrodeposited platinum-iridium on carbon fiber electrodes.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same author

Value of Reduced Time to Repair for Combat Ocular Trauma.

Ophthalmology·2025
Same author

A Comprehensive Research Dissemination Model for Polymer-Based Neural Interfaces.

IEEE transactions on bio-medical engineering·2025
Same author

Restoration of Sight with Electronic Retinal Prostheses.

Annual review of vision science·2025

Related Experiment Video

Updated: Mar 5, 2026

Methodology for Biomimetic Chemical Neuromodulation of Rat Retinas with the Neurotransmitter Glutamate In Vitro
12:56

Methodology for Biomimetic Chemical Neuromodulation of Rat Retinas with the Neurotransmitter Glutamate In Vitro

Published on: December 19, 2017

8.2K

Strategies to improve stimulation efficiency for retinal prostheses.

Navya S Davuluri, Kiran Nimmagadda, Artin Petrossians

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |March 23, 2017
    PubMed
    Summary

    Researchers explored efficient retinal stimulation strategies for vision restoration in Retinitis Pigmentosa (RP) patients. Optimized electrical pulse control and novel electrode materials significantly improved power efficiency for retinal prostheses.

    More Related Videos

    Techniques for Processing Eyes Implanted With a Retinal Prosthesis for Localized Histopathological Analysis
    12:01

    Techniques for Processing Eyes Implanted With a Retinal Prosthesis for Localized Histopathological Analysis

    Published on: August 2, 2013

    20.4K
    Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
    10:50

    Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

    Published on: June 21, 2022

    2.2K

    Related Experiment Videos

    Last Updated: Mar 5, 2026

    Methodology for Biomimetic Chemical Neuromodulation of Rat Retinas with the Neurotransmitter Glutamate In Vitro
    12:56

    Methodology for Biomimetic Chemical Neuromodulation of Rat Retinas with the Neurotransmitter Glutamate In Vitro

    Published on: December 19, 2017

    8.2K
    Techniques for Processing Eyes Implanted With a Retinal Prosthesis for Localized Histopathological Analysis
    12:01

    Techniques for Processing Eyes Implanted With a Retinal Prosthesis for Localized Histopathological Analysis

    Published on: August 2, 2013

    20.4K
    Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
    10:50

    Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

    Published on: June 21, 2022

    2.2K

    Area of Science:

    • Biomedical Engineering
    • Neuroscience
    • Ophthalmology

    Background:

    • Retinitis Pigmentosa (RP) causes progressive vision loss.
    • Retinal prostheses aim to restore vision in RP patients.
    • Efficient retinal stimulation is crucial for prosthesis efficacy.

    Purpose of the Study:

    • To identify optimal strategies for efficient retinal electrical stimulation.
    • To compare voltage-controlled versus current-controlled stimulation.
    • To evaluate the power efficiency of a high surface area electrode.

    Main Methods:

    • In-vivo experiments in rats.
    • Electrical stimulation of the retina.
    • Measurement of electrically evoked responses (EERs) in the superior colliculus.
    • Comparison of EER strength and power efficiency under different stimulation parameters and electrode materials.

    Main Results:

    • Voltage-controlled pulses were more efficient for short durations (< 1 ms).
    • Current-controlled pulses were more efficient for longer durations (> 1 ms).
    • A high surface area platinum-iridium electrode significantly reduced power consumption compared to standard electrodes.

    Conclusions:

    • Stimulation pulse control strategy impacts efficiency based on pulse width.
    • Advanced electrode materials offer substantial power savings for retinal prostheses.
    • Findings contribute to developing more effective visual prosthetics for RP.