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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
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Is heart failure with midrange ejection fraction similar to preserved ejection fraction? For
1Servicio de Medicina Interna General, ICMiD Hospital Clínic-IDIBAPS, Universidad de Barcelona, Barcelona, España.
Revista Clinica Espanola
|March 23, 2017
Summary
Heart failure (HF) is now classified into three categories based on left ventricular ejection fraction (LVEF). The new midrange LVEF category (40-49%) shows characteristics more aligned with HF with preserved LVEF.
Area of Science:
- Cardiology
- Echocardiography
- Heart Failure Pathophysiology
Background:
- Heart failure (HF) classification traditionally relies on left ventricular ejection fraction (LVEF).
- Established categories include HF with reduced LVEF (HFrEF) and HF with preserved LVEF (HFpEF).
- Recent advancements introduced a midrange LVEF category.
Purpose of the Study:
- To analyze the characteristics of the newly defined HF with midrange LVEF (40-49%).
- To compare the midrange LVEF group with established HF classifications.
- To determine the clinical and echocardiographic similarities of HFmrEF.
Main Methods:
- Echocardiographic assessment of LVEF.
- Classification of heart failure patients into HFrEF, HFmrEF, and HFpEF.
- Comparative analysis of clinical and echocardiographic parameters across the three groups.
Main Results:
- The HF with midrange LVEF category (40-49%) has been recently defined.
- Current data suggests HFmrEF shares more similarities with HFpEF than HFrEF.
- This finding impacts diagnostic and therapeutic strategies for heart failure.
Conclusions:
- The distinct characteristics of HFmrEF warrant specific consideration in clinical practice.
- Reclassifying HF based on LVEF provides a more nuanced understanding of the disease.
- Further research is needed to fully elucidate the pathophysiology and optimal management of HFmrEF.
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