Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Human Genetics01:28

Human Genetics

1.8K
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
1.8K
Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

4.6K
The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
4.6K
Understanding Sleep01:11

Understanding Sleep

1.8K
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
1.8K
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

1.2K
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
1.2K
Primary Motives: Sleep, Sex, and Pain Avoidance01:24

Primary Motives: Sleep, Sex, and Pain Avoidance

6.3K
Primary motives such as sleep, sex, and pain avoidance are crucial drivers of behavior in humans and animals. These motives ensure survival, reproductive success, and overall well-being by prompting actions that meet essential bodily needs.
Sleep is a fundamental physiological drive that fosters a state of restfulness crucial for several bodily functions. It facilitates body restoration, the process by which the body repairs, rejuvenates, and maintains itself during sleep, including memory...
6.3K
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

500
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
500

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Epigenetics as a mechanism of lineage extinction and relapse of B-cell lymphoma treated with CD19 CAR T-cell therapy.

Blood neoplasia·2026
Same author

From breadth to depth in clinical artificial intelligence evaluation.

Nature biomedical engineering·2026
Same author

CD48 expression in T-lymphoblastic leukemia/lymphoma and mature T-cell neoplasms: role in detecting measurable residual disease and potential confounders, a single-institution retrospective review.

American journal of clinical pathology·2026
Same author

Deoxygenative Arylation of Allylic/Benzylic Esters through Cooperative Photoredox/Nickel Catalysis.

Organic letters·2026
Same author

Update of germ line RUNX1 variant curation rules: version 3.1.

Blood advances·2026
Same author

Generation of an induced pluripotent stem cell line from a patient with Loeys-Dietz syndrome.

Stem cell research·2026
Same journal

Cichlid fish as a model for understanding social dysfunction.

Current opinion in neurobiology·2026
Same journal

On aims and methods in field neuroethology: Investigating neural mechanisms of behavior in semi-natural and natural contexts.

Current opinion in neurobiology·2026
Same journal

Neurobiological interfaces connecting environmental change to monarch butterfly migration.

Current opinion in neurobiology·2026
Same journal

Learning how to experience the world: From circuits to cell types to genes.

Current opinion in neurobiology·2026
Same journal

Editorial overview for neurobiology of disease 2026.

Current opinion in neurobiology·2026
Same journal

Optical voltage imaging: ready to spark systems neuroscience.

Current opinion in neurobiology·2026
See all related articles

Related Experiment Video

Updated: Mar 5, 2026

Noninvasive, High-throughput Determination of Sleep Duration in Rodents
07:33

Noninvasive, High-throughput Determination of Sleep Duration in Rodents

Published on: April 18, 2018

8.3K

Human genetics and sleep behavior.

Guangsen Shi1, David Wu2, Louis J Ptáček1

  • 1Kavli Institute for Fundamental Neuroscience, Weill Institute of Neuroscience, Department of Neurology, University of California San Francisco, San Francisco, CA 94143, United States; Howard Hughes Medical Institute, University of California San Francisco, San Francisco, CA 94143, United States.

Current Opinion in Neurobiology
|March 23, 2017
PubMed
Summary
This summary is machine-generated.

Human genetics is unraveling the mysteries of sleep, revealing heritable traits affecting sleep timing, duration, and brainwave patterns. These genetic insights are crucial for understanding sleep mechanisms and related neurological disorders.

More Related Videos

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
05:59

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Published on: October 20, 2023

3.2K
The Sleep Nullifying Apparatus: A Highly Efficient Method of Sleep Depriving Drosophila
06:06

The Sleep Nullifying Apparatus: A Highly Efficient Method of Sleep Depriving Drosophila

Published on: December 14, 2020

4.3K

Related Experiment Videos

Last Updated: Mar 5, 2026

Noninvasive, High-throughput Determination of Sleep Duration in Rodents
07:33

Noninvasive, High-throughput Determination of Sleep Duration in Rodents

Published on: April 18, 2018

8.3K
Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
05:59

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Published on: October 20, 2023

3.2K
The Sleep Nullifying Apparatus: A Highly Efficient Method of Sleep Depriving Drosophila
06:06

The Sleep Nullifying Apparatus: A Highly Efficient Method of Sleep Depriving Drosophila

Published on: December 14, 2020

4.3K

Area of Science:

  • Neuroscience
  • Genetics
  • Sleep Science

Background:

  • Sleep's fundamental role in health and cognition remains incompletely understood.
  • Recent advancements in human genetics offer new avenues for exploring sleep biology.
  • Heritability of various sleep features suggests a strong genetic basis for sleep regulation.

Purpose of the Study:

  • To summarize recent discoveries in human genetics related to sleep.
  • To highlight genetic variations influencing sleep timing, duration, and electroencephalogram (EEG) patterns.
  • To discuss the implications of genetic findings for understanding sleep disorders.

Main Methods:

  • Review of recent scientific literature on human genetics and sleep.
  • Analysis of genetic variations associated with specific sleep phenotypes.
  • Exploration of links between genetic factors and neurological conditions affecting sleep.

Main Results:

  • Identification of specific genetic variations impacting sleep timing and duration.
  • Characterization of genetic influences on electroencephalogram (EEG) patterns during sleep.
  • Emerging evidence connecting genetic factors to sleep disturbances in Autism Spectrum Disorder (ASD) and Alzheimer's Disease (AD).

Conclusions:

  • Human genetics is pivotal in deciphering the biological underpinnings of sleep.
  • Understanding genetic variations in sleep can illuminate disease mechanisms.
  • Future research directions include exploring genetic complexities and therapeutic targets for sleep disorders.