Related Experiment Video
Updated: Mar 5, 2026
04:53
Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
Published on: October 18, 2024
1.6K
Obstructive sleep apnoea accelerates FEV1 decline in asthmatic patients
Tsai-Yu Wang1, Yu-Lun Lo1, Shu-Min Lin1
1Pulmonary Disease Research Centre, Department of Thoracic Medicine, Chang Gung Memorial Hospital, Chang Gung University, School of Medicine, 199 Tun-Hwa N. Rd., Taipei, Taiwan.
BMC Pulmonary Medicine
|March 23, 2017
Summary
Obstructive sleep apnoea (OSA) significantly accelerates lung function decline in asthma patients. Continuous positive airway pressure (CPAP) treatment can mitigate this decline, particularly in severe OSA cases.
Area of Science:
- Pulmonology
- Sleep Medicine
Background:
- Increasing prevalence of both obstructive sleep apnoea (OSA) and asthma.
- Limited understanding of OSA's impact on lung function in asthma patients.
Purpose of the Study:
- To investigate the effect of OSA severity on lung function decline in asthma patients.
- To evaluate the efficacy of continuous positive airway pressure (CPAP) treatment in mitigating lung function decline in asthmatic patients with OSA.
Main Methods:
- Retrospective analysis of 466 patients from a sleep laboratory.
- Focus on 77 asthma patients with over 5 years of follow-up.
- Categorization into groups based on apnoea-hypopnea index (AHI) severity.
Main Results:
- Asthma patients with severe OSA (AHI > 30/h) showed a significantly greater decline in FEV1 (72.4 ml/year) compared to those with mild-to-moderate OSA (41.9 ml/year) or no OSA (24.3 ml/year).
- Continuous positive airway pressure (CPAP) treatment led to a significant reduction in FEV1 decline among patients with severe OSA.
- Apnoea-hypopnea index (AHI) was identified as the sole independent factor influencing FEV1 decline.
Conclusions:
- Asthma patients with OSA experience accelerated lung function decline.
- CPAP therapy is effective in reducing FEV1 decline in severe OSA patients with asthma.
More Related Videos
Related Concept Videos
01:21Sleep Apnea
667
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
667
01:20Asthma: Pathogenesis and Management
1.5K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.5K
01:30Asthma-IV: Diagnostic and Management
3.3K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.3K
01:26Asthma-II: Pathophysiology and Classification
4.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.7K
01:24Asthma-III: Symptoms and Complications
3.5K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
3.5K
01:26COPD: Management Using Bronchodilators and Corticosteroids
982
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
982