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Seizures: Classification01:13

Seizures: Classification

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Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
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Focal Seizures
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Epilepsy and Seizures: Overview01:24

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Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
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A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
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The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
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A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
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Recurrence Risk of Febrile Seizures in Children.

J Agrawal1, P Poudel1, G S Shah1

  • 1Department of Pediatrics, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.

Journal of Nepal Health Research Council
|March 23, 2017
PubMed
Summary

Identifying children with febrile seizure (FS) at risk for recurrence is crucial. Male gender and age under one year are significant risk factors for FS recurrence in children.

Keywords:
Epilepsy; febrile seizure; recurrence.

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Area of Science:

  • Pediatrics
  • Neurology
  • Epidemiology

Background:

  • Febrile seizures (FS) are common in childhood.
  • Identifying children at high risk for FS recurrence is essential for targeted management.
  • Understanding risk factors aids in providing appropriate care and parental guidance.

Purpose of the Study:

  • To identify risk factors associated with febrile seizure recurrence in children.
  • To inform clinical practice regarding the management of children with febrile seizures.

Main Methods:

  • A prospective hospital-based study was conducted in Nepal.
  • 92 children aged 6 months to 6 years with febrile seizures were enrolled.
  • Clinical, investigation, treatment, and outcome parameters were analyzed.

Main Results:

  • Recurrence of febrile seizures was observed in approximately one-third of cases.
  • Significant risk factors for recurrence included male gender (p=0.088) and age less than 1 year (p=0.003).
  • Most recurrences occurred within one year of the initial febrile seizure.

Conclusions:

  • Febrile seizures are more prevalent in males.
  • Male gender and younger age (under 1 year) are significant predictors of febrile seizure recurrence.
  • Early identification of these risk factors can guide clinical interventions.