Related Experiment Video
Updated: Mar 5, 2026

Author Spotlight: Advancing Syphilis Research — Innovations in Treponema pallidum Cultivation and Genetic Engineering
Published on: January 24, 2025
Prevalence and factors associated with syphilis in a Reference Center
Natália Carolina Rodrigues Colombo Gomes1, Denise Andrade Pereira Meier1, Flávia Meneguetti Pieri1
1Departamento de Enfermagem, Universidade Estadual de Londrina, Londrina, PR, Brasil.
Syphilis rapid testing (RT) in Brazil found a 6.3% prevalence, with higher rates in men. Key risk factors include young adult age, lower education, and substance use, highlighting the need for targeted prevention strategies.
Area of Science:
- Public Health
- Infectious Diseases
- Epidemiology
Background:
- Rapid testing (RT) for syphilis improves early diagnosis and treatment access for vulnerable populations.
- Centers for Testing and Counseling (CTC) play a crucial role in managing sexually transmitted infections (STDs).
Purpose of the Study:
- To assess the prevalence of syphilis among individuals utilizing a Center for Testing and Counseling (CTC).
- To identify sociodemographic and behavioral factors associated with syphilis infection in this population.
Main Methods:
- A cross-sectional study analyzed data from 5,509 individuals who underwent syphilis RT between June 2012 and December 2014 in Southern Brazil.
- Prevalence and odds ratios were calculated using OpenEpi to determine associations between independent variables and syphilis cases.
Main Results:
- The overall prevalence of syphilis was 6.3%, with higher rates in males (7.5%) than females (4.3%).
- Syphilis was significantly associated with ages 25-34, lower education levels, and single marital status.
- Associated behavioral factors included men who have sex with men, drug use (alcohol, marijuana, cocaine, crack), and a history of STDs.
Conclusions:
- Intensified syphilis prevention and control strategies are essential, particularly for identified vulnerable populations.
- Targeted interventions should address the specific risk factors identified in this study population.
Related Concept Videos
Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Sexually Transmitted Infections
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Ethics in Research

