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Updated: Mar 5, 2026

Author Spotlight: Exploring Cellular Zinc Regulation Through ZnT1 Functionality
Published on: June 2, 2023
Light-Controlled Release and Uptake of Zinc Ions in Solution by a Photochromic Terthiazole-Based Ligand
Juliette Guérin1, Anne Léaustic1, Jérôme Berthet2
1Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO), CNRS, Univ Paris Sud, Université Paris-Saclay, 91405, Orsay, France.
Abstract:
We have synthesized and fully characterized a photochromic zinc complex with a terphenylthiazole-based ligand with a salen-like cavity. The solution stability of the complex was found to be greatly dependent on the state of the photochromic ligand and an interesting photo-triggered release and uptake of zinc ions was found as well as monitored by its fluorescence. The contrasting stability difference of the zinc complex between its two isomeric states was rationalized by DFT calculations.

