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Induction of Ocular Surface Inflammation and Collection of Involved Tissues
Published on: August 4, 2022
Ocular Involvement in Children with Inflammatory Bowel Disease
Samuele Naviglio1, Fulvio Parentin, Silvia Nider
1*Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, Italy; and †Institute for Maternal and Child Health IRCCS "Burlo Garofolo," Trieste, Italy.
Ocular manifestations in pediatric inflammatory bowel disease (IBD) are uncommon. Asymptomatic uveitis in children with IBD appears less prevalent than previously thought, with no observed complications from unrecognized cases.
Area of Science:
- Ophthalmology
- Pediatric Gastroenterology
- Inflammatory Bowel Disease
Background:
- Limited data exists on ocular manifestations in pediatric inflammatory bowel disease (IBD).
- Previous reports suggest a high prevalence of asymptomatic uveitis, but its clinical significance and recommended follow-up are unclear.
Purpose of the Study:
- To evaluate the prevalence of ocular manifestations in children with IBD.
- To determine the necessity of routine ophthalmologic follow-up for pediatric IBD patients.
Main Methods:
- Ophthalmologic evaluations were conducted on children with IBD at a pediatric gastroenterology referral center.
- Evaluations included history review, slit-lamp, and fundoscopic examinations.
Main Results:
- Of 94 children (median age 13.4 years), 1.06% had a history of uveitis, and only one had asymptomatic uveitis detected.
- One patient developed a posterior subcapsular cataract due to corticosteroid treatment.
- No ocular complications from unrecognized uveitis were found.
Conclusions:
- Asymptomatic uveitis in pediatric IBD patients may be less common than previously reported.
- The study did not find uveitis in patients without a prior clinical diagnosis.
- No ocular complications were observed in children with IBD during the study period.
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