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Updated: Dec 24, 2025

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
A case report: Liraglutide as a novel treatment option in late dumping syndrome
Sonja Chiappetta1, Christine Stier
1Department of Obesity and Metabolic Surgery, Sana Klinikum Offenbach, Offenbach am Main, Germany.
Rationale:
Postprandial hyperinsulinemic hypoglycemia, known as late dumping syndrome, is a rare but often misdiagnosed complication after gastric surgery. The pathophysiological mechanisms are poorly understood and the treatment of this syndrome is challenging.
Patient Concerns:
New-onset postsurgical late dumping syndrome after Toupet fundoplication.
Diagnoses:
Sigstad Score, OGTT, CGM.
Interventions:
Daily subcutaneous injection of liraglutide (0.6 mg and 1.2 mg).
Outcomes:
Reduction in fasting and postprandial peak insulin level with improvement in symptomatic hypoglycemic events.
Lessons:
Liraglutide may be a novel treatment option for postprandial hyperinsulinemic hypoglycemia after gastric surgery.
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