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Updated: Mar 5, 2026
Real-Time Assessment of Spinal Cord Microperfusion in a Porcine Model of Ischemia/Reperfusion
Published on: December 10, 2020
Spinal cord protection during thoracoabdominal aortic replacement: spinal cord perfusion maintenance
Gaku Uchino1, Keiji Yunoki1, Naoya Sakoda1
1Department of Cardiovascular Surgery, Hiroshima Shimin Hospital, Hiroshima, Japan.
Objectives:
Spinal cord protection during thoracoabdominal aortic surgery is challenging for surgeons. We performed thoracoabdominal replacement using a strategy for maintaining spinal cord perfusion pressure. Here, we report our experience with this procedure and the surgical outcomes.
Methods:
Between January 2000 and December 2014, 130 patients [male: 91 (74.6%), female: 39 (25.4%); mean age: 66.6 ± 12.8 years] underwent thoracoabdominal replacement using cardiopulmonary bypass at Hiroshima Shimin Hospital, Japan. The surgical outcomes of these patients were analysed.
Results:
The in-hospital mortality rate of all patients was 2.5%. The incidence of postoperative paraplegia was 3.8%. Aortic event-free survival rates at 1, 3 and 5 years were 98.2%, 93.9% and 80.7%, respectively.
Conclusions:
The present study suggests that our strategy for maintaining spinal cord perfusion pressure provides acceptable outcomes.
