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Longitudinal Intravital Imaging Through Clear Silicone Windows

Longitudinal Intravital Imaging Through Clear Silicone Windows

Published on: January 5, 2022

Silicone granulomas with ulcers.

Lisa R Rothman¹, Randie H Kim, Shane A Meehan

¹Ronald O. Perelman Department of Dermatology, NYU School of Medicine, NYU Langone Medical Center.

Dermatology Online Journal

|March 23, 2017

Summary

This summary is machine-generated.

This case study highlights a rare instance of ulcerative silicone granuloma in a transgender woman following illegal silicone injections. The condition was exacerbated by hemodialysis, leading to challenging treatment due to comorbidities.

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Area of Science:

Dermatology
Plastic Surgery
Nephrology

Background:

Silicone granulomas are known complications of cosmetic silicone injections, particularly when administered by non-physicians.
Ulcerative forms of silicone granulomas are infrequently reported in medical literature.

Observation:

A 42-year-old transgender woman presented with woody induration and persistent buttock ulcers, developing 10 years after illegal silicone injections.
Histopathology confirmed silicone granuloma, with ulcers potentially linked to prolonged weight-bearing during hemodialysis and compromised vascular supply.

Findings:

The patient's condition involved extensive tissue reaction to illegally administered silicone.
Ulceration of the silicone granuloma was a rare and complicating feature.

Implications:

This case underscores the risks associated with non-medical grade silicone injections and the importance of qualified practitioners.
Management of silicone granulomas is complex, especially in patients with significant comorbidities like end-stage renal disease and congestive heart failure.