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Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics
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A diagnostic challenge
D Ismail1, G Langman, S D Orpin
1Department of Dermatology, Dudley NHS Foundation Trust, West Midlands, United Kingdom. dinawismail@gmail.com.
Abstract:
A 74 year-old woman presented with a 9 month history of a slowly enlarging exophytic lesion over her left nasal alar. Examination revealed a firm, cystic mass fixed to underlying skin. It was pedunculated with occasional superficial telangiectasia and a violaceous hue. A differential diagnosis of dermoid or sebaceous cyst, dermatofibroma, and neurofibroma was considered. Histopathological examination confirmed the rare diagnosis of chondroid syringoma (CS), which has a reported incidence of 0.01- 0.098% of excised skin tumors. It is unusual for CS to present in an elderly woman, as these benign primary skin tumors normally present in adult males. Dermoscopy does not reveal any specific features and the diagnosis is difficult to make based on clinical examination alone.
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