Related Experiment Video
Updated: Mar 5, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Delay in diagnosis of acral melanoma
Roberto Rheingantz da Cunha Filho1, Leandra Matte, Ricardo Hohmann Camina
1School of Medical Sciences, Universidade do Oeste de Santa Catarina (UNOESC), Joaçaba, Santa Catarina, Brazil. robertodermatologista@yahoo.com.br.
Abstract:
We report a 41-year-old woman presented with a 4-year history of an exuberant, erythematous tumor, with necrotic appearance of the right distal toe. The histopathology examination showed a nodular-ulcerative melanoma, with bone infiltration. Widespread metastases including the right ovary, peritoneum, and right breast were present. The patient was misdiagnosed for almost 4 years as having onychomycosis, ingrown nail and pyogenic granuloma.

