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Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
Published on: December 3, 2019
[Spatial and temporal characteristics of HIV/AIDS in Hubei province, 2010-2013]
Abstract:
Objective: To understand the spatial and temporal distribution of HIV/AIDS in Hubei province, and provide scientific evidence for the prevention and control of AIDS. Methods: GeoDa software was used for autocorrelation analysis, SatScan 9.2 software was used for statistical analysis of spatial scanning, and finally geographic information system was used for visualization. Results: A total of 6 952 HIV/AIDS cases were reported during 2010-2013 in Hubei, and the spatial autocorrelation analysis showed that Global Moran's I index was 0.266 (P<0.05), indicating that there was a positive spatial autocorrelation of HIV/AIDS. Global Moran's I index increased year by year (P<0.05), indicating that the increased spatial aggregation of HIV/AIDS during 2010-2013. The local Moran's I index showed that " high-high" clustering areas were in Wuhan, and the number of " high-high" clustering areas increased during 2010-2013. Moreover, the " high-high" clustering areas expanded from Wuhan to surrounding areas. Spatial and temporal scan analysis revealed that 19 counties in Wuhan, Huangshi, Ezhou, Xianning with a radius of 60.01 km (LLR=625.14, RR=3.23) were the main spatial and temporal clustering area during 2012-2013. Conclusion: The spatial changes of HIV/AIDS seemed to be regular from 2010 to 2013 in Wuhan, spatial correlation at provincial level decreased and the " high-high" clustering areas gradually expanded from Wuhan to surrounding areas, indicating that it is necessary to strengthen the AIDS prevention and control in these areas in Hubei.

