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Related Concept Videos

Dementia01:30

Dementia

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Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
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Association Areas of the Cortex01:21

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Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
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Alzheimer's Disease: Overview01:26

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
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Alzheimer's Disease: Treatment01:22

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Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
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Prosopagnosia01:24

Prosopagnosia

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Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
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Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

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The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
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Related Experiment Video

Updated: Mar 5, 2026

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
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[Frontotemporal dementia].

Peter Johannsen1, Hanne Gottrup, Jette Stokholm

  • 1peter.johannsen.01@regionh.dk.

Ugeskrift for Laeger
|March 24, 2017
PubMed
Summary

Frontotemporal dementia (FTD) is a group of neurodegenerative diseases affecting the brain's frontal and temporal lobes. Recent advances have updated its clinical, genetic, and pathological classifications.

Area of Science:

  • Neurology
  • Neuroscience
  • Pathology

Background:

  • Frontotemporal dementia (FTD) encompasses clinical syndromes stemming from neurodegenerative processes in the frontal and temporal lobes.
  • Understanding of FTD has evolved, necessitating revisions in its classification.

Purpose of the Study:

  • To review the current understanding and classification of frontotemporal dementia (FTD).

Main Methods:

  • Literature review of recent advancements in FTD research.
  • Analysis of updated clinical, genetic, and pathological classifications.

Main Results:

  • Significant progress in FTD knowledge has led to revised diagnostic criteria.
  • Updated classifications reflect a more nuanced understanding of FTD subtypes.

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Last Updated: Mar 5, 2026

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Conclusions:

  • Current classification systems for FTD are dynamic and evolving.
  • Continued research is crucial for refining the understanding and management of FTD.