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Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
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The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
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Related Experiment Video

Updated: Mar 5, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
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[Ectopic thyroid tissue with a primary carcinoma].

Pernille Hammershøj Jensen1, Anette Pedersen Pilt, Hans-Erik Wittendorff

  • 1hammershoej7913@gmail.com.

Ugeskrift for Laeger
|March 24, 2017
PubMed
Summary
This summary is machine-generated.

Ectopic thyroid carcinoma is rare. This case highlights perivesical ectopic papillary thyroid carcinoma in a man with a normal thyroid gland, successfully treated with radioactive iodine therapy.

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Area of Science:

  • Endocrinology
  • Surgical Pathology
  • Oncology

Background:

  • Ectopic thyroid tissue, resulting from abnormal embryologic development, is rare with a prevalence of 1 in 100,000-300,000.
  • Malignant transformation within ectopic thyroid tissue is exceptionally uncommon.

Observation:

  • A rare case of perivesical ectopic papillary thyroid carcinoma was identified in a 76-year-old male.
  • The patient presented with a histologically normal orthotopic thyroid gland.

Findings:

  • Total thyroidectomy confirmed normal thyroid tissue without neoplastic involvement.
  • The patient received radioactive iodine treatment for the ectopic carcinoma.
  • Follow-up scintigraphy showed no signs of residual or active disease.

Implications:

  • This case underscores the importance of considering ectopic thyroid carcinoma in differential diagnoses, even with a normal orthotopic gland.
  • It demonstrates the efficacy of standard thyroid cancer treatment protocols, including radioactive iodine, for ectopic presentations.
  • Further research into the embryogenesis and oncogenesis of ectopic thyroid tissue is warranted.