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Published on: March 25, 2019
Current applications and future prospects of nanomaterials in tumor therapy
Yu Huang1, Chao-Qiang Fan1, Hui Dong1
1Department of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing, People's Republic of China.
Abstract:
Tumors are one of the most serious human diseases and cause numerous global deaths per year. In spite of many strategies applied in tumor therapy, such as radiation therapy, chemotherapy, surgery, and a combination of these treatments, tumors are still the foremost killer worldwide among human diseases, due to their specific limitations, such as multidrug resistance and side effects. Therefore, it is urgent and necessary to develop new strategies for tumor therapy. Recently, the fast development of nanoscience has paved the way for designing new strategies to treat tumors. Nanomaterials have shown great potential in tumor therapy, due to their unique properties, including passive targeting, hyperthermia effects, and tumor-specific inhibition. This review summarizes the recent progress using the innate antitumor properties of metallic and nonmetallic nanomaterials to treat tumors, and related challenges and prospects are discussed.
Insights
New nanomaterials offer promising strategies for tumor therapy, overcoming limitations of traditional treatments like chemotherapy and radiation. This review explores metallic and nonmetallic nanomaterials for enhanced cancer treatment.
Area of Science:
- Oncology
- Nanomedicine
- Materials Science
Background:
- Tumors remain a leading cause of global mortality despite existing therapies like chemotherapy, radiation, and surgery.
- Current treatments face limitations including multidrug resistance and significant side effects.
- Developing novel therapeutic strategies is crucial for effective tumor management.
Purpose of the Study:
- To review recent advancements in utilizing the inherent antitumor properties of metallic and nonmetallic nanomaterials.
- To discuss the potential of nanomaterials in overcoming current tumor therapy challenges.
- To explore future prospects and challenges in nanomedicine for cancer treatment.
Main Methods:
- Review of current scientific literature on nanomaterials in cancer therapy.
- Analysis of studies focusing on metallic and nonmetallic nanomaterials.
- Discussion of nanomaterial properties relevant to tumor treatment, including passive targeting and hyperthermia.
Main Results:
- Nanomaterials exhibit unique properties beneficial for tumor therapy, such as targeted delivery and thermal ablation.
- Metallic and nonmetallic nanomaterials demonstrate innate antitumor capabilities.
- The application of nanoscience provides novel avenues for overcoming treatment resistance and side effects.
Conclusions:
- Nanomaterials represent a significant advancement in developing next-generation tumor therapies.
- Harnessing the properties of metallic and nonmetallic nanomaterials offers a promising approach to combat cancer.
- Further research is needed to address challenges and fully realize the potential of nanomedicine in oncology.
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