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Updated: Mar 5, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
Pleural amyloidosis imitating pleural malignancy
Frith Coolbear1, Ana-Maria Bilawich1, Jonathan Tongson2
1Department of Radiology, Vancouver General Hospital and University of British Columbia, Vancouver, BC, Canada.
Abstract:
CT chest performed to investigate dyspnea and malaise in an 83 year old man demonstrated bilateral circumferential pleural thickening highly suspicious for pleural mesothelioma or metastatic pleural malignancy. Histopathology of a subsequent pleural biopsy returned a diagnosis of pleural amyloid. This case identifies pleural amyloid as a rare differential consideration for diffuse pleural thickening; the difficulties in distinguishing pleural amyloid from pleural malignancy are highlighted.
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