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Induction and Assessment of Exertional Skeletal Muscle Damage in Humans
Published on: December 11, 2016
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Perspectives on Exertional Rhabdomyolysis
Eric S Rawson1, Priscilla M Clarkson2, Mark A Tarnopolsky3
1Department of Health, Nutrition and Exercise Science, Messiah College, One College Avenue Suite 4501, Mechanicsburg, PA, 17055, USA. erawson@messiah.edu.
Sports Medicine (Auckland, N.Z.)
|March 24, 2017
Summary
Exertional rhabdomyolysis is a serious condition, but creatine monohydrate does not appear to cause it. Proper exercise prescription and medical history are key to preventing this muscle damage condition.
Area of Science:
- Sports Medicine
- Exercise Physiology
- Toxicology
Background:
- Exertional rhabdomyolysis is a potentially fatal condition linked to various factors including unaccustomed exercise and toxins.
- Research and media attention highlight the importance of understanding its causes and prevention.
- Identifying precipitating factors is crucial for clinical management and public health.
Purpose of the Study:
- To review existing literature on exertional rhabdomyolysis.
- To identify key precipitating factors associated with the condition.
- To specifically examine the role of creatine monohydrate supplementation.
Main Methods:
- Literature search of PubMed and SPORTDiscus databases.
- Keywords included: rhabdomyolysis, muscle damage, creatine, creatine supplementation, creatine monohydrate, phosphocreatine.
- References of identified papers were also reviewed; meta-analysis was not performed.
Main Results:
- Exertional rhabdomyolysis can occur due to improper exercise prescription, punishment, or incomplete medical histories.
- Creatine monohydrate was not found to be a precipitating factor in the reviewed literature.
- Healthcare professionals must recognize signs for prompt treatment.
Conclusions:
- Proper exercise testing and prescription according to professional standards are essential for minimizing rhabdomyolysis risk.
- Awareness and prompt recognition of exertional rhabdomyolysis signs are critical for patient outcomes.
- Further research may be warranted to explore the multifactorial nature of exertional rhabdomyolysis.
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