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Prostaglandin-E-producing hepatocellular carcinoma with hypercalcemia.
T Ikeda1, S Tozuka, Y Hasumura
1Second Department of Internal Medicine, School of Medicine, Tokyo Medical and Dental University, Japan.
Cancer
|May 1, 1988
Summary
This study presents a case of liver cancer (hepatocellular carcinoma) producing prostaglandin E, leading to severe hypercalcemia. Treatment with indomethacin temporarily lowered calcium, but the tumor
Area of Science:
- Oncology
- Endocrinology
- Pathology
Background:
- Hypercalcemia is a complex metabolic disturbance often associated with malignancy.
- Malignant hypercalcemia can arise from various mechanisms, including parathyroid hormone-related protein or bone metastases.
- This case explores an alternative etiology involving prostaglandin E production by a liver tumor.