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X-linked lymphoproliferative disease: a karyotype analysis
1Paediatric Research Unit, United Medical and Dental School of Guy's Hospital, London Bridge, UK.
Cytogenetics and Cell Genetics
|January 1, 1988
Abstract:
X-linked lymphoproliferative disease (XLP) is triggered by Epstein-Barr virus. This virus is also associated with Burkitt lymphoma, a tumor that carries specific chromosome translocations. No such chromosome translocations have been observed in an analysis of XLP-derived cell lines. One XLP patient was found also to have Klinefelter syndrome, having inherited two copies of his maternal XLP-carrying X chromosome.