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Published on: October 23, 2018
[Evaluation of oro-cecal transit time in patients with irritable bowel syndrome with cereal products intolerance]
Aleksandra Błońska1, Paulina Konrad1, Jan Chojnacki1
1Department of Clinical Nutrition and Gastroenterology Diagnostics Medical University of Łódź, Poland.
Abstract:
The main symptoms of irritable bowel syndrome (IBS) include abnormal frequency of bowel movements. On this basis, three main clinical types of the disease have been distinguished, i.e.: constipation (IBSC), diarrhea (IBS-D) and mixed-type (IBS-M) in accordance with the Rome III criteria. These disorders mainly affect the colon, but symptoms related to upper gastrointestinal tract are also often observed.
Aim:
The aim of the study was to assess the oro-caecal transit time in patients with irritable bowel syndrome with IgG-dependent hypersensitivity to cereal products.
Materials And Methods:
The study was performed in three 30-person groups, aged 27-48 years (38.3 ± 10.4), in whom three types of IBS were diagnosed basing on the Rome III criteria . The control group consisted of 30 subjects without gastrointestinal symptoms. Orocaecal transit time was measured by hydrogen breath test using lactulose and Gastro + Gastrolyzer (Bedfont).
Results:
The mean oro-caecal transit time was respectively in the groups: controls - 86,3 ± 5,95 min., IBS-C - 95,8 ±10,9 min. (p<0,05), IBS-D - 77,8 ± 8,21 min (p<0,01) and IBS-M - 80,6 ± 14,2 (p>0,05). There was a positive correlation between the transit time and disorder severity in IBS-C (p=0,05) group and negative in IBS-D (p<0,001) group. No significant correlation was found in IBS-M group (p=0,864).
Conclusions:
Disturbed digestic passage in the upper gastrointestinal tract may affect the clinical manifestation of irritable bowel syndrome.
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