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Synteny and Evolution

Synteny and Evolution

John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
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Mapping Mammalian 3D Genome Interactions with Micro-C-XL

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Published on: November 3, 2023

SynMap2 and SynMap3D: web-based whole-genome synteny browsers.

Asher Haug-Baltzell¹, Sean A Stephens², Sean Davey³

¹Genetics GIDP, University of Arizona, Tucson AZ, USA.

Bioinformatics (Oxford, England)

|March 24, 2017

Summary

This summary is machine-generated.

New web-based tools, SynMap2 and SynMap3D, visualize whole genome synteny, overcoming limitations of existing methods for comparative genomics research.

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Area of Science:

Comparative genomics
Bioinformatics
Computational biology

Background:

Existing synteny visualization tools are limited in scope or usability.
There is a need for accessible, genome-wide synteny visualization.

Purpose of the Study:

To develop user-friendly, web-based tools for whole genome synteny visualization.
To provide researchers with accessible platforms for exploring genomic relationships.

Main Methods:

Development of SynMap2 (two genomes) and SynMap3D (three genomes) using modern web technologies.
Integration with the Comparative Genomics Platform (CoGe) database and user data upload functionality.
Provision of responsive web-based and virtual reality visualization environments.

Main Results:

SynMap2 and SynMap3D enable visualization of synteny across entire genomes.
Tools offer access to a large database of over 30,000 genomes.
No installation is required, enhancing accessibility and ease of use.

Conclusions:

SynMap2 and SynMap3D address limitations of current synteny visualization tools.
These tools facilitate exploration of genome-wide synteny patterns.
The web-based nature ensures broad accessibility for the research community.