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Updated: Mar 5, 2026

Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury
Published on: July 17, 2016
Abstract:
Acute kidney injury (AKI) is a syndrome characterized by the rapid loss of the glomerular filtration (GF) with consecutive retention of nitrogen-containing substances. It includes conditions from mild injury with slight metabolic derangements to oligoanuric failure with life-threatening metabolic disruption. 130 subjects with this renal injury were hospitalized at the Ist Department of Internal Medicine of the University Hospital of Louis Pasteur and the Medical Faculty of the University of Pavol Jozef Šafárik in Košice in the Slovak Republic in the years 2013, 2014 and 2015. It is resulted from the analysis of patients that they were mainly elderly patients whose AKI developed in chronic kidney disease (CKD) terrain. The most common reason was hypovolemia caused by dehydratation (44.62 %).Key words: acute kidney injury - dehydratation.
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