Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Parathyroid Glands00:59

The Parathyroid Glands

5.5K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
5.5K
Cancer02:18

Cancer

55.2K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
55.2K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

4.1K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
4.1K
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

6.5K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
6.5K
Synthesis and Functions of Calcitonin00:51

Synthesis and Functions of Calcitonin

5.1K
Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
5.1K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

9.0K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
9.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Left atrial function in class III obesity: a pilot study using two-dimensional speckle tracking echocardiography.

BMC cardiovascular disorders·2026
Same author

Effect of semaglutide with metformin for weight loss and fertility in polycystic ovary syndrome (PCOS) patients with obesity: A pilot prospective study.

Clinical nutrition ESPEN·2025
Same author

Effect of Submaximal Doses of Semaglutide in Patients with Obesity on Metabolic Profile and Serum Levels of Adipocytokines.

Pharmaceuticals (Basel, Switzerland)·2025
Same author

National guidelines for diagnosis and treatment of osteoporosis in Slovakia.

Archives of osteoporosis·2025
Same author

Carboxypeptidase B1 in dialyzed chronic kidney disease patients.

Scientific reports·2025
Same author

Association of trabecular bone score corrected for tissue thickness with glucose metabolism in acromegaly.

Frontiers in endocrinology·2024

Related Experiment Video

Updated: Mar 5, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

2.4K

[Parathyroid cancer].

Ivana Ságová, Matej Stančík, Peter Kentoš

    Vnitrni Lekarstvi
    |March 24, 2017
    PubMed
    Summary

    Parathyroid cancer is a rare endocrine malignancy. Early diagnosis and radical surgery are crucial for improving patient outcomes, as other treatments are often ineffective.

    Area of Science:

    • Endocrinology
    • Oncology

    Background:

    • Parathyroid cancer is a rare endocrine malignancy, accounting for less than 1% of primary hyperparathyroidism cases.
    • Etiology is largely unknown, but risk factors include neck irradiation, end-stage renal failure, and genetic mutations like HPRT2/CDCT73.
    • The disease often presents indolently but can progress to local invasion and metastasis.

    Purpose of the Study:

    • To highlight the clinical presentation and diagnostic challenges of parathyroid cancer.
    • To emphasize the importance of early and accurate diagnosis in managing this rare malignancy.
    • To review current treatment strategies and their efficacy.

    Main Methods:

    • Literature review of parathyroid cancer diagnosis and treatment.
    • Analysis of clinical characteristics and risk factors.

    More Related Videos

    Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
    07:12

    Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

    Published on: August 17, 2022

    5.0K
    Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
    03:55

    Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

    Published on: June 9, 2023

    1.1K

    Related Experiment Videos

    Last Updated: Mar 5, 2026

    Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
    03:57

    Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

    Published on: July 14, 2023

    2.4K
    Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
    07:12

    Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

    Published on: August 17, 2022

    5.0K
    Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
    03:55

    Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

    Published on: June 9, 2023

    1.1K
  • Evaluation of treatment outcomes for surgery, chemotherapy, and radiotherapy.

    • Main Results:

    • Parathyroid cancer presents with severe, resistant hypercalcemia often requiring intensive therapy and dialysis.
    • Radical surgery is the primary effective treatment.
    • Chemotherapy and radiotherapy generally show limited efficacy.

    Conclusions:

    • Early and correct diagnosis of parathyroid carcinoma is critical for improving patient morbidity and mortality.
    • Surgical intervention remains the cornerstone of parathyroid cancer treatment.
    • Further research into the etiology and novel therapeutic approaches is warranted.