Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

In vivo partial body activation analysis using filtered neutron beam.

C Chung1

  • 1Institute of Nuclear Science, National Tsing Hua University, Taiwan, R.O.C.

International Journal of Radiation Applications and Instrumentation. Part A, Applied Radiation and Isotopes
|January 1, 1988
PubMed
Summary

This study details a new method for in vivo prompt gamma-ray activation analysis using a mobile nuclear reactor. It enables sensitive, low-dose mercury detection in body organs for rapid diagnostics.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Targeting Neutrophil Extracellular Traps to inhibit Colon Cancer Tumor Necrosis and Metastasis.

bioRxiv : the preprint server for biology·2025
Same author

Timing of radiotherapy (RT) after radical prostatectomy (RP): long-term outcomes in the RADICALS-RT trial (NCT00541047).

Annals of oncology : official journal of the European Society for Medical Oncology·2024
Same author

Low household income increases the risk of tuberculosis recurrence: a retrospective nationwide cohort study in South Korea.

Public health·2023
Same author

Treatment outcome, recurrence and safety of multidrug-resistant TB treated with low-dose linezolid.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2023
Same author

Treatment outcomes and safety of bedaquiline, delamanid, and linezolid in multidrug-resistant TB.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2023
Same author

Concordance of diagnostic modalities in atypical skin and soft tissue infections in hospitalized patients.

Archives of dermatological research·2022

Area of Science:

  • Nuclear Physics
  • Medical Diagnostics
  • Analytical Chemistry

Background:

  • Prompt gamma-ray activation analysis (PGAA) is a nuclear technique for elemental analysis.
  • In vivo applications require sensitive methods with minimal radiation exposure.
  • Accurate elemental quantification in biological tissues is crucial for medical diagnostics.

Purpose of the Study:

  • To describe a facility for in vivo PGAA using a mobile nuclear reactor.
  • To investigate neutron flux uniformity in a liquid phantom for accurate irradiation.
  • To demonstrate the determination of toxic mercury concentration in organs with high sensitivity and low radiation dose.

Main Methods:

  • Utilized a mobile nuclear reactor to generate a filtered neutron beam.

Related Experiment Videos

  • Employed a liquid phantom to simulate biological tissue for irradiation studies.
  • Measured neutron flux distribution under unilateral and bilateral irradiation conditions.
  • Applied PGAA principles to quantify elemental mercury concentration.

    • Main Results:

    • Established a functional facility for in vivo PGAA.
    • Characterized neutron flux distribution within the phantom, assessing uniformity.
    • Achieved sensitive detection of mercury with minimal radiation doses.
    • Demonstrated the potential for rapid diagnostic irradiation.

    Conclusions:

    • The developed facility is suitable for in vivo elemental analysis.
    • The method allows for sensitive and low-dose determination of toxic elements like mercury in organs.
    • This technique holds promise for rapid medical diagnostics and health monitoring.