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Legionella pneumophila Pneumonia in Two Infants Treated with Adrenocorticotropic Hormone
Yael Shachor-Meyouhas1, Sarit Ravid2, Suheir Hanna3
1Pediatric Infectious Diseases Unit, Ruth Rappaport Children's Hospital, Rambam Health Care Campus, Haifa, Israel.
Insights
Adrenocorticotropic hormone treatment for infantile spasms may increase the risk of Legionella pneumonia in infants. This rare pneumonia complication was observed in two infants shortly after initiating this epilepsy treatment.
Area of Science:
- Pediatrics
- Infectious Diseases
- Neurology
Background:
- Infantile spasms are a severe epileptic disorder in infants.
- Adrenocorticotropic hormone (ACTH) is a common treatment for infantile spasms.
- Legionella pneumophila is an uncommon cause of pneumonia in pediatric patients.
Abstract:
Patients with infantile spasms, an intractable epileptic disorder, often are treated with adrenocorticotropic hormone. Legionella pneumophila is a rare cause of pneumonia in children. We describe 2 infants with Legionella pneumonia whose infection occurred within 1 month after starting adrenocorticotropic hormone.
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