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Published on: April 21, 2017
Pediatric arterial ischemic stroke: Epidemiology, risk factors, and management
Ryan J Felling1, Lisa R Sun1, Emily C Maxwell2
1Johns Hopkins University School of Medicine, Department of Neurology, Baltimore, MD 21287, United States.
Insights
Pediatric arterial ischemic stroke (AIS) is a rare but serious condition in children. Early diagnosis and understanding risk factors are crucial for effective management and improved outcomes in pediatric stroke patients.
Area of Science:
- Neurology
- Pediatrics
- Vascular Medicine
Background:
- Pediatric arterial ischemic stroke (AIS) is an uncommon cause of neurologic disability in children.
- Consequences include hemiparesis, intellectual disabilities, and epilepsy.
- Causes and risk factors differ significantly from adult stroke.
Purpose of the Study:
- To review the epidemiology and risk factors of pediatric AIS.
- To outline consensus-based evaluation and management practices.
- To discuss outcomes in neonates and children with AIS.
Main Methods:
- Literature review of pediatric arterial ischemic stroke.
- Analysis of epidemiological data and risk factors.
- Synthesis of current consensus-based practices for diagnosis and management.
Main Results:
- Pediatric AIS has unique causes and risk factors compared to adults.
- Delayed diagnosis is a common challenge.
- Established guidelines exist for evaluation and management.
Conclusions:
- Continued research and specialized centers are vital for advancing pediatric stroke care.
- Improved understanding of risk factors can lead to earlier diagnosis and better outcomes.
- Further investigation is needed to address persistent uncertainties in pediatric AIS.
Abstract:
Pediatric arterial ischemic stroke (AIS) is an uncommon but important cause of neurologic morbidity in neonates and children, with consequences including hemiparesis, intellectual disabilities, and epilepsy. The causes of pediatric AIS are unique to those typically associated with stroke in adults. Familiarity with the risk factors for AIS in children will help with efficient diagnosis, which is unfortunately frequently delayed. Here we review the epidemiology and risk factors for AIS in neonates and children. We also outline consensus-based practices in the evaluation and management of pediatric AIS. Finally we discuss the outcomes observed in this population. While much has been learned in recent decades, many uncertainties sill persist in regard to pediatric AIS. The ongoing development of specialized centers and investigators dedicated to pediatric stroke will continue to answer such questions and improve our ability to effectively care for these patients.
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